NCMIR Multi-Scale Imaging Project
The NCMIR Multi-Scale Imaging Portal (the original Telescience-based Portal) consolidates access for controlling instruments remotely, managing data, and controlling batch jobs with a single login and password. The Portal walks the user through the complex process of remote data acquisition via Telemicroscopy; Globus-enabled parallel tomographic reconstruction; advanced visualization, segmentation, and data processing tools; and transparent deposition of data products into federated libraries of cellular structure. Key features of the Portal include personalized user information, collaboration tools such as chat and shared white boards, and automatic storage of data and job tracking tools.
NIEHS Environmental Health Science Data Resource Portal
The NIEHS (National Institute for Environmental Health Sciences) Environmental Healh Science Data Resource Portal is a GIS-based site that providetools and information for those who are addressing the consequences of natural disasters such as Hurricanes Katrina and Rita by supporting the decision-making process related to: Identifying sources and routes of contaminants; Evaluating the potential for future exposures; Assessing human exposures that occurred in the immediate aftermath of the hurricanes; and Assessing the immediate and longer term health impacts associated with these exposures.
Biomedical Informatics Research Network Portal
The Biomedical Informatics Research Network (BIRN) Portal provides BIRN members with a single sign on web portal to access data grid files, computation grid resources, and a variety of collaboration tools to facilitate the scientific needs of BIRN researchers. Non-BIRN participants may access the portal through a guest registration.
Branfman Family Foundation Collaboration Portal
Cooperative activities between Branfman Family Foundation investigators have brought new opportunities for multidisciplinary collaborations to study Parkinsonian-like pathogenic processes and evaluate possible therapeutic approaches using in vitro and in vivo model systems. The use of existing and extended IT infrastructure (specifically a data sharing environment, neuroinformatics tools, and shared imaging technologies) is facilitating communication between our institutions. Moreover, these Parkinsonian-specific collaborations are fostering dialogue between multidisciplinary researchers who might have otherwise never shared ideas or information.
NCI National Brain Cancer Model Collaborative Network (nBCMn) Portal
Most textbooks describe glial cells as subservient to neuronal function in the CNS, however, more recently neuroscientists have determined that glia are active participants in CNS function. Great progress has been made in studies of glial cell biochemistry, structure and physiology. Nonetheless, we understand very little about the properties of glial cells elicited by cancer promoting lesions in distinct microenvironments of the brain. The present collaborative project between MMHCC participants and UCSD-NCMIR researchers is permitting us to address distinct questions about the morphology, distribution and molecular constituents associated with normal and tumor-involved tissues in transgenic mouse models. The ability to examine the properties of glia using imaging technologies developed at NCMIR will facilitate and understanding of the spatial and morphological changes in neuronal and glial cells that impact malignancy. Thus, we are working together to further characterize the transgenic astrocytoma pathology using novel methods, which have proven superior to traditional methods of characterizing neuronal and glial morphology, distribution and associated molecular machinery.
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